Curve behavior

Questions
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1

Dear Datagrok team,
I would like to inquire about the behavior of Curve functionality.

In order to show the reproducibility of an assay experiments, I have stored multiple curve data sets in the same color within a single cell. I wrote the sample data in the bottom of this post for your reference.

I’ve noticed that in a cell in grid, only one curve is visible by default. However, when I either double-click the cell or use the MultiCurveViewer, both curves become visible.

Is it possible to modify the JSON configuration to display both curves simultaneously within the grid cell? I wonder if you colud point out in case I set incorrect parameters in JSON.

image
image597×308 17.5 KB

Best regards,
Kosuke

{"series": [{"showCurveConfidenceInterval": false, "points": [{"x": "0.000200", "y": "100"}, {"x": "0.000600", "y": "88.9"}, {"x": "0.00200", "y": "71.0"}, {"x": "0.00620", "y": "7.57"}, {"x": "0.0186", "y": "-59.2"}, {"x": "0.0560", "y": "-98.0"}, {"x": "0.168", "y": "-99.8"}, {"x": "0.500", "y": "-99.9"}], "fitFunction": "sigmoid", "pointColor": "#2ca02c", "fitLineColor": "#2ca02c", "errorModel": "combined", "lineStyle": "dotted", "droplines": ["IC50"]}, {"showCurveConfidenceInterval": false, "points": [{"x": "0.000200", "y": "99.5"}, {"x": "0.000599", "y": "104"}, {"x": "0.00619", "y": "-0.634"}, {"x": "0.0186", "y": "-75.3"}, {"x": "0.0559", "y": "-98.4"}, {"x": "0.168", "y": "-99.8"}, {"x": "0.500", "y": "-99.9"}], "fitFunction": "sigmoid", "pointColor": "#2ca02c", "fitLineColor": "#2ca02c", "errorModel": "combined", "lineStyle": "dotted", "droplines": ["IC50"]}], "chartOptions": {"showStatistics": [], "xAxisName": "Conc.", "yAxisName": "Activity", "logX": true, "logY": false, "title": "Dose-Response curves"}}

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2

Hi Kosuke,

We’ve just investigated the issue together with @drizhinashvili and identified the cause — it was related to cache invalidation, which prevented the curves from rendering properly in the grid.

Unfortunately, there’s no simple workaround on your side, other than predefining the calculated parameters directly in the JSON.

If this issue is important to you, we can update the Curves package to a new version that includes the fix, so you can start using it right away. Just let me know, and we’ll proceed with the update. Otherwise, the fix will be included in the upcoming Datagrok v1.26 release (to be precise, in the new Curves package version that will come with 1.26).

Kind regards,
Dmytro

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3

Dear Dmytro,
Thank you for your prompt investigation and feedback. This issue is not urge at this moment for our side, so I can wait until next update without any problems. I appreciate your warm suggestion to fix promptly.
Best,
Kosuke

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